Retrosynthetic Analysis: Predict reactants for a target product
Output is rendered by RDKit.js directly from the model's raw SMILES,
shown beneath each structure. Ketcher is used only for drawing the input
target — it never touches the predicted output. Compare the green raw
string against the drawing: they should match.
checking server…
Model:
Each accuracy is on that model's own benchmark, named beneath it —
the two are not directly comparable. Hover for detail.
Built on ReactionT5v2 (Sagawa & Kojima,
J. Cheminform.2025,
doi:10.1186/s13321-025-01075-4,
MIT-licensed), fine-tuned on Pistachio reaction data
(NextMove Software). This web interface built independently.
Beam width:10
Show top-k:6
The first three are classical textbook reactions both models handle.
The green one is a 2026 patent target — switch models and re-run to
compare.
Predicted reactant sets
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